Protein Interaction Analysis

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Protein-protein interactions (PPIs) are established when protein molecules physically contact with each other through hydrogen or hydrophobic bonds, Van der Waals forces, ionic forces, or even covalent bonds. This phenomenon underlies a wide range of essential cellular events such as signal transduction, molecular transport and various metabolism pathways. PPIs are also the basic of many diseases. Therefore, PPIs have been studied extensively in the area of bioscience and medical research.

Profacgen has established in our lab a series of assays to help with your Protein Interaction Analysis research, including high throughput interaction screening assays such as Yeast two-hybrid screening and phage display technology, interaction strength and kinetics assays such as Surface Plasmon Resonance (SPR). Each approach has its own advantages and weaknesses in terms of sensitivity and specificity. While you can choose the techniques you prefer, we can also help recommend.